Combination of oridonin and TRAIL induces apoptosis in uveal melanoma cells by upregulating DR5
AIM: To investigate the inhibitory effect of the INOSITOL combined use of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and oridonin on choroidal melanoma cell lines, and to explore its underlying mechanism.METHODS: MUM-2B and C918 cells were treated with different concentrations of TRAIL and oridonin, and MTT assay used to evalua